Brian Hie

Laboratory of Evolutionary Design

Developing biological AI for human good at Stanford University

Research

Our mission is to ensure that the AI revolution in biology occurs in a way that benefits humanity.
We aim to design biology that counteracts evolving threats and accomplishes useful new functions.

Progress

Some of our research progress is described in the selected publications below.

A high-level programming language for generative biology with Proto
Making biology programmable
Genome modeling and design across all domains of life with Evo 2
A unifying model of biological information
Semantic design of functional de novo genes from a genomic language model
Going beyond the observable evolutionary universe
Generative design of novel bacteriophages with genome language models
Designing complete genomes
Efficient generation of epitope-targeted antibodies with Germinal
Rapid antibody design
View all publications